Approximately 70% of patients in need of Hematopoietic Stem Cells transplant (HSCT) lack HLA-matched relatives and may require to obtain HSC from HLA-matched unrelated voluntary donors registered in databases in the country or around the world. Probability of finding HLA-matched unrelated donors is greater among the same ethnic and racial background with higher chance for a successful transplant. This emphasizes the importance of establishing a national registry for donor recruitment in the country. It would be also possible for donors to join the World Marrow Donor Assembly (WMDA) through national registries.
ISCDR (Iranian Stem Cell Donor Registry) is a national center for recruiting, training, registering and maintaining of hematopoietic stem cell voluntary donors. People who are willing to donate Stem cells in their bone marrow or peripheral blood if they are found to match a patient needing a HSCT.
This center was established in February 2009 through Iranian Blood Transfusion Organization (IBTO) but the official activity of donor recruitment begun on 15 June 2010 (World Blood Donor Day). IBTO is a nonprofit organization, attached to the Ministry of Health and Medical Education, responsible for the collection, processing, testing and distribution of blood and blood products in Iran. Therefore, ISCDR was established according to IBTO duties for donor recruitment and training to donate HSC to unrelated patients. ISCDR was named Sepas Center in Farsi language which means Thanks.
If needed, physicians in transplant centers can conduct their patients without a family donor to the ISCDR to increase his chance for finding a donor.
- To provide centralized information on the HLA
phenotypes and other relevant data of unrelated stem cell
donors in Iran for the benefit of all patients.
- To educate and recruit adequate potential HSC donors.
- To maximize the chance of finding a suitable unrelated stem cell donors among Iranians.
- To minimize and coordinating the efforts required search process to find suitable donors.